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Iron chelation AND neurodegeneration

Showing 1 - 25 of 2,164

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Stroke Trial in Bordeaux, Lille, Montpellier (Magnetic Resonance Imaging (MRI), Deferiprone treatment)

Recruiting
  • Stroke
  • Magnetic Resonance Imaging (MRI)
  • Deferiprone treatment
  • Bordeaux, France
  • +2 more
Jun 9, 2022

Sickle Cell Disease Trial in Amsterdam (Deferasirox 360 MG)

Recruiting
  • Sickle Cell Disease
  • Deferasirox 360 MG
  • Amsterdam, Meibergdreef 9, Netherlands
    Amsterdan UMC location AMC
May 23, 2022

Amyotrophic Lateral Sclerosis Trial in France (Deferiprone, Placebo Oral Tablet)

Active, not recruiting
  • Amyotrophic Lateral Sclerosis
  • Angers, France
  • +14 more
Nov 4, 2022

Testing of NBIA Genes: Analysis of Genetic Heterogeneity and

Completed
  • Neurodegeneration With Brain Iron Accumulation (NBIA)
  • Establishment of mitochondrial markers
  • Sequencing tests
  • Talence, France
    Centre Hospitalier Universitaire de Bordeaux
Nov 7, 2022

Huntington's Disease.

Recruiting
  • Huntington Disease
  • 7T MRI-scan
  • +3 more
  • Leiden, Zuid-Holland, Netherlands
    Leiden University Medical Centre
Sep 5, 2022

Thalassemia, Iron Overload Trial in Oakland (Combo Chelation with Deferasirox (Exjade) and Deferoxamine (DFO))

Completed
  • Thalassemia
  • Iron Overload
  • Combo Chelation with Deferasirox (Exjade) and Deferoxamine (DFO)
  • Oakland, California
    CHRCO
Jul 20, 2021

Thalassemia Major Trial in New York, Bangkok, Chiang Mai (DST-0509, Jadenu, Exjade)

Completed
  • Thalassemia Major
  • New York, New York
  • +3 more
Jan 31, 2022

Beta Thalassemia Major Trial in Tirana (Emeramide)

Completed
  • Beta Thalassemia Major
  • Tirana, Albania
    University Hospital Center "Mother Theresa" Tirana
Aug 20, 2021

Transfusional Iron Overload, Iron Overload, Iron Chelation Trial (SPD602, Deferasirox)

Withdrawn
  • Transfusional Iron Overload
  • +6 more
  • (no location specified)
Jun 1, 2021

Intellectual Disability, Rubinstein-Taybi Syndrome, Cystic Fibrosis Trial in Bordeaux (Ex-vivo approach concerning 25 patients,

Not yet recruiting
  • Intellectual Disability
  • +6 more
  • Ex-vivo approach concerning 25 patients
  • In-vitro approach concerning 25 patients
  • Bordeaux, France
    Hopital Pellegrin
Jan 23, 2023

Brain Iron Toxicity and Neurodegeneration - A 7T MRI Study

Enrolling by invitation
  • Prodromal Alzheimer's Disease
  • Mild Cognitive Impairment
  • MRI at 7T
  • Nottingham, East Midland, United Kingdom
    Nottingham University Hospitals NHS Trust
Jul 28, 2021

Iron Overload Due to Repeated Red Blood Cell Transfusions Trial in Worldwide (SPD602)

Terminated
  • Iron Overload Due to Repeated Red Blood Cell Transfusions
  • Los Angeles, California
  • +11 more
Jun 11, 2021

Assess Iron Chelation Therapy in Chronic Iron Overload

Completed
  • Chronic Iron Overload
  • Iron chelator
  • Winnenden, Baden Wuerttemberg, Germany
  • +102 more
Jun 29, 2022

THALASSEMIA MAJOR Trial in Oakland (Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary

Completed
  • THALASSEMIA MAJOR
  • Blood Draw/Semen Exam
  • +2 more
  • Oakland, California
    UCSF Benioff Children's Hospital Oakland
Dec 22, 2020

Iron Overload, Oxidative Stress, Thalassemia Major Trial in Bani Suwayf, Mecca (Omega 3, Nigella Sativa Oil, Hydroxyurea)

Completed
  • Iron Overload
  • +2 more
  • Omega 3
  • +5 more
  • Banī Suwayf, Egypt
  • +3 more
Jan 25, 2021

Transfusional Iron Overload, Beta-thalassemia Trial in Worldwide (SPD602 (FBS0701, SSP-004184))

Completed
  • Transfusional Iron Overload
  • Beta-thalassemia
  • SPD602 (FBS0701, SSP-004184)
  • Oakland, California
  • +8 more
May 30, 2021

Parkinson Disease Trial in Worldwide (Deferiprone, Placebo)

Active, not recruiting
  • Parkinson Disease
  • Innsbruck, Austria
  • +24 more
Mar 9, 2021

Natural History Patient-reported Outcome Measures

Recruiting
  • Neurodegeneration With Brain Iron Accumulation (NBIA)
    • Portland, Oregon
      Oregon Health & Science University
    Oct 5, 2020

    Cardiac Function in Patients With Hereditary Hemochromatosis

    Completed
    • Hereditary Hemochromatosis
      • Bethesda, Maryland
        National Institutes of Health Clinical Center
      Jan 27, 2023

      Parkinson Disease, Progressive Supranuclear Palsy Trial in France (7 Tesla MRI)

      Not yet recruiting
      • Parkinson Disease
      • Progressive Supranuclear Palsy
      • 7 Tesla MRI
      • Aix-en-Provence, France
      • +5 more
      Nov 24, 2023

      MDS Trial in Beijing (Lenalidomide, Azacitidine)

      Not yet recruiting
      • Myelodysplastic Syndromes
      • Beijing, China
        Peking union medical college hospital
      Aug 16, 2023

      Myelodysplastic Syndrome, Iron Overload Trial in Canada, United States (Deferasirox)

      Completed
      • Myelodysplastic Syndrome
      • Iron Overload
      • Birmingham, Alabama
      • +47 more
      Jul 21, 2021

      Pantothenate Kinase-Associated Neurodegeneration Trial (Deferiprone)

      No longer available
      • Pantothenate Kinase-Associated Neurodegeneration
      • (no location specified)
      Nov 9, 2022

      MPAN Trial (Passive Stretching, Mobilization, Muscle strengthening)

      Not yet recruiting
      • MPAN
      • Passive Stretching
      • +3 more
      • (no location specified)
      Jan 20, 2023

      SAH, Dementia Trial in Iowa City (Deferiprone pill, , Montreal Cognitive Assessment)

      Recruiting
      • SAH
      • Dementia
      • Deferiprone pill
      • +2 more
      • Iowa City, Iowa
        Univesity of Iowa Hospital and Clinics
      Mar 7, 2022